2024

Dry Eye Disease & TL-925 MOA

Entrant Company

Cognition Studio, Inc.

Category

Video, Commercial & Film - Medical

Client's Name

Telios Pharma

Country / Region

United States

This animation was one half of a 20x30-foot conference booth display. The circular video portal was 9'-6" and displayed on 1.63 mm LED tiles. The portal itself was set upon a raised 3-tier platform to a full elevation of 12'-6".

DED & TL-925 MOA story flow:

The Awakening: A healthy eye blinks normally with proper tear production.

The Invasion: Mast cells migrate to the lacrimal gland, degranulating and causing inflammation.

The Assault: Degranulating mast cells invade lacrimal acinar cells, damaging them and reducing tear production.

The Escalation: B cells activate, releasing IL-17. T cells activate, releasing cytokines and escalating inflammation.

The Aftermath: Ongoing mast cell, B cell, and T cell activity severely impair tear production, causing dry eye disease with erratic blinking.

The Remedy: TL-925 droplets restore moisture, reducing inflammation and returning the eye to normal blinking/movement.

The Fine Print: The screen dims, and the eye goes out of focus. The FDA disclaimer text animates in, and the animation ends.

Start again.

Credits

Co-founder, Ex. Dir. of Science Storytelling
David W. Ehlert, MAMS, CMI, FAMI
Lead Animator + Illustrator
Joshua Bird, MS, CMI
Assoc. Dir. of Science Storytelling
Jared Travnicek, MA, CMI
Sr. Medical Animator + Illustrator
Brandon Keehner, MS, CMI
Medical Animator + Illustrator
Katie Harvey, MS
Sr. Medical Animator + Illustrator
Val Altounian, CMI
Sr. Medical Animator + Illustrator
Regina Milner, MS, CMI
Project Manager for Science Storytelling
Julie Devi Coats, MS, CMI, CAPM
Assoc. Dir. of Science Storytelling
Inessa Stanishevskaya, MSCMBC, CMI
Lead Designer, Brand + Interactive
Amanda Grage
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